Dopamine Genes and Rapid Reality Adaptation in Thinking

Objective

To determine if genetic variants related to dopamine processing in the brain impact the processing of memories according to their relation with ongoing reality

Description

Our brains are able to adapt to the unexpected using an inbuilt network that makes predictions about the world and monitors how those predictions turn out. An area at the front of the brain, called the orbitofrontal cortex, plays a central role and studies have shown that patients with damage to this area confuse memories with reality and continue to anticipate events that are no longer likely to happen.

This study seeks to determine if genetic variants in the dopamine processing pathway impact this process in normal, healthy volunteers.

This study is being conducted in conjunction with the Center of Cognitive Neurorehabilitation at the Geneva University Hospital in Switzerland and based on ongoing research on the underlying mechanisms impacting the processing of memories according to their relation with ongoing reality.

Since we are using this study to learn about collaborating with a university and hospital, some of the raw data will live with the university and hospital researchers.
Please see http://bit.ly/hbPFzD for more information on this research.

Inclusion Criteria

1) Absence of psychological or neurologic disorders (ie. bipolar disorder, schizophrenia, epilepsy, parkinson's, prior stroke, traumatic brain injury, dementia) 2) Informed consent of all participants 3) Availability of personal genetic SNP information 4) Willingness to provide background demographic data 5) Willingness to complete memory filtering tasks (approx, 30-40 minutes)

Day 1: Receive Participation Code

Receive your anonymized code from the study organizers, usually within 24 hours of joining the study

Day 1: Memory Filtering Task

Complete the Memory Filtering Task which takes approximately 40 minutes: http://www.memoryfiltering-task.net/

Day 1: Demographic Survey

Complete the Demographics and Perceptual Survey which takes approximately 10 minutes: http://evalens-cmu.unige.ch/evasys/indexstud.php (PASSWORD: testbs)

Summary

This study offers the ability to participate in cutting-edge memory research with Dr. Armin Schnider, a worldwide leader in neurology, currently at the University of Geneva and the NIH in Bethesda MD. The study intends to provide a personalized interpretation of your results by email when the study is complete.

Discussion

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esilver I never received my codename, so can't get started on the study

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gbiggers

gbiggers Hey LJ! Welcome to the cool study. We are pretty enthused about this cooperation between Genomera, DIYGenomics, and the Neuroscientists at University of Geneva, Switzerland.

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