Aging: risk reduction for common aging conditions through monitoring & intervention

Objective

Establish baseline markers of wellness and relevant interventions in human aging from a personalized perspective. Intervene in the case of blood-based markers that are out-of-bounds.

Description

A longitudinal personalized aging study. Here is an opportunity to apply the dozens of genome-wide association studies which relate to a variety of general and specific conditions of aging in a comprehensive manner for preventive medicine. Genomic data is linked with corresponding measures of phenotypic or physical biomarkers and testing relevant interventions for phenotype amelioration.

I. Top twenty biological mechanisms of aging in GWAS include: neurodegenerative disease, osteoporosis, IGF-1/Insulin signaling, lipoprotein metabolism, inflammation, immune system function, DNA damage repair, telomere length, transcription (ex: RNA editing), catabolism, mitochondrial health, cell cycle/stem cell health, protein function, blood operations

II. Top twenty phenotypic biomarkers of aging include: blood pressure and hypertension, cholesterol (HDL/LDL/triglycerides; LDL particle size), BMI, Framingham Risk Score, VO2 max, erythrocyte glycoslyation, telomere length, lymphocyte growth capability, granulocyte strength

More information here

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oldandangry Blood markers

oldandangry My mother has been through any number of tests - we expect that they will provide sufficient information for the start of this study.

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aaronvollrath the required blood test for this study is the direct labs test of the month and is priced at $59.00. if i remember correctly this is about $40 less than the regular price.

melanie thanks Aaron - you're right, the DirectLabs test is usually marked down in December ($59). i am ordering mine now and will get it fulfilled in early january to capture my annual blood marker levels. https://directlabs.com/ShoppingCart/tabid/2146/language/en-US/Default.aspx

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herbaldoc I have some basic labs in my mountain of medical information that go back as far as my birth. CBC, that sort of thing.

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EriGentry I'm excited for this study! Many thanks for putting it together! I will have tests done the last week of February. How can I enter data?

melanie Hopefully the Aging Tracker will allow a csv or text file upload (you may need to convert your PDF), or allow data entry of specific items

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Organizers

melanie

12 Studies

In Progress

Genome Variants

rs1000290, rs1001254, rs1002666, rs1003533, rs10036031, rs10069397, rs1007147, rs10106137, rs10114818, rs10128711, rs10153531, rs10179640, rs10195252, rs10201482, rs1023782, rs10252600, rs1033867, rs1036819, rs10401969, rs1040566, rs1042034, rs10435884, rs10488360, rs10490733, rs10493379, rs10493485, rs10494076, rs10494366, rs10496112, rs10500784, rs10502177, rs10503669, rs10506540, rs10507486, rs10508257, rs10510303, rs10511887, rs10514211, rs10515522, rs10521157, rs10524523, rs1063192, rs1063539, rs10744835, rs10760894, rs10761731, rs10761779, rs10778213, rs10789021, rs10822890, rs10823112, rs10830963, rs10843049, rs1084651, rs10880908, rs10885122, rs10888267, rs10895656, rs10901850, rs10903420, rs10923931, rs10924270, rs10947262, rs10957534, rs10957743, rs10980705, rs10990103, rs10997307, rs11014166, rs11024074, rs11049255, rs11049256, rs11053781, rs11065987, rs11071657, rs11073328, rs11074359, rs11082159, rs11105354, rs11105364, rs11105368, rs11105378, rs1111875, rs11136000, rs11136341, rs11150040, rs11157721, rs11159647, rs11191548, rs11206344, rs11206510, rs11220462, rs11245204, rs11250168, rs1143634, rs1151640, rs11558471, rs11577939, rs11591741, rs11597086, rs11597390, rs11597670, rs11600570, rs11600717, rs11600908, rs11601402, rs11601425, rs11601692, rs11601890, rs11602134, rs11602504, rs11602934, rs11604194, rs11604887, rs11605078, rs11605096, rs11605737, rs11605924, rs11606211, rs11606336, rs11606746, rs11607594, rs11607622, rs11607690, rs11607704, rs11607718, rs11607747, rs11607834, rs11607852, rs11610206, rs11611975, rs11613352, rs11615979, rs11625406, rs11634135, rs11634397, rs11641122, rs11642341, rs11642677, rs11649653, rs11663391, rs11664087, rs1169288, rs1169313, rs11708067, rs11710086, rs11710916, rs1171278, rs11713185, rs11776767, rs11778674, rs11785060, rs11785349, rs11812285, rs11869286, rs11887534, rs11895934, rs11920090, rs11996075, rs12003047, rs12027135, rs12027550, rs12035891, rs1203981, rs12064952, rs12086247, rs12094387, rs12198299, rs12202794, rs12258078, rs12286037, rs12328675, rs12355784, rs12364051, rs12404920, rs12444419, rs12446827, rs1245072, rs12474609, rs12489747, rs12499249, rs12501388, rs12579302, rs12585627, rs1260326, rs12605030, rs12606866, rs12629971, rs12654264, rs12654739, rs12670798, rs12678919, rs12696304, rs12698138, rs12721226, rs12779790, rs12854616, rs12875277, rs12891954, rs12896790, rs12906592, rs12910887, rs12914235, rs12916, rs12935091, rs12952455, rs12956332, rs12958645, rs12963356, rs12965352, rs12967135, rs12967168, rs13107325, rs1316506, rs13217795, rs1322048, rs13235506, rs13238203, rs13266634, rs13277069, rs13288161, rs13292136, rs1333049, rs1333416, rs1333420, rs1340573, rs1343981, rs1348807, rs1350102, rs1353005, rs1355202, rs1362512, rs1367117, rs1377638, rs1378942, rs1383636, rs1387153, rs1393942, rs1393943, rs1399904, rs1399906, rs1399910, rs1399915, rs1399916, rs1416280, rs1420356, rs1436013, rs1442138, rs1442709, rs1455311, rs1456669, rs1466930, rs1466931, rs1468271, rs147295, rs1475398, rs1495741, rs1515724, rs1515741, rs1515743, rs1531343, rs1532085, rs1533484, rs1534957, rs1535487, rs1540874, rs1543505, rs1550650, rs1552224, rs1564348, rs1568020, rs1568282, rs157580, rs157581, rs1579333, rs1588907, rs16119, rs16120, rs16126, rs16131, rs16132, rs16138, rs16139, rs16140, rs16141, rs16142, rs16143, rs16147, rs16148, rs16473, rs16474, rs16475, rs16478, rs16823061, rs16832246, rs16832279, rs16847897, rs16850255, rs16879258, rs1689800, rs16922827, rs16942887, rs16944, rs16948048, rs16957640, rs16972414, rs16981163, rs16996148, rs17029781, rs17073844, rs17073955, rs1709544, rs17107115, rs17111051, rs17145738, rs17201113, rs17249754, rs17293880, rs17294019, rs17297422, rs17321515, rs17367504, rs17369174, rs17369209, rs17374047, rs17401847, rs174546, rs174550, rs17463551, rs1748195, rs17531898, rs17532157, rs17532254, rs17532375, rs17532479, rs17532884, rs17541000, rs17541153, rs17593986, rs17603387, rs17606668, rs17610557, rs17610915, rs17611093, rs17611127, rs17612378, rs176765, rs17679678, rs17702471, rs1778231, rs17799174, rs1780324, rs1800562, rs1800630, rs1800795, rs1800961, rs1801253, rs1801282, rs1804160, rs1805086, rs1810636, rs1811483, rs181362, rs1815739, rs182052, rs1850000, rs1866218, rs1872500, rs1878064, rs1883025, rs1885472, rs1892534, rs1894605, rs1923249, rs1927914, rs1935949, rs1950705, rs1954971, rs1955389, rs1955390, rs1988459, rs1991391, rs2000999, rs2003168, rs201825, rs202906, rs2029637, rs2035912, rs2042086, rs2042831, rs2043544, rs2048801, rs2068888, rs2072183, rs2073618, rs2073724, rs2075650, rs2081687, rs2087324, rs210332, rs2131879, rs2131925, rs213490, rs2143571, rs2144300, rs2154380, rs2156552, rs2157719, rs2179706, rs2188186, rs2191349, rs2203490, rs2219078, rs2221516, rs2221517, rs2241880, rs2247056, rs2247549, rs2247647, rs2255141, rs2274899, rs2277862, rs2281135, rs2290159, rs2293607, rs2293776, rs2293889, rs2305421, rs231130, rs231362, rs2322292, rs2333491, rs2334207, rs2338104, rs2344495, rs2344922, rs234577, rs2362932, rs2373115, rs2374983, rs2383208, rs2384550, rs2387653, rs2387952, rs2394287, rs240970, rs2410845, rs2411759, rs2412710, rs2423969, rs2423970, rs243021, rs2440514, rs2455455, rs2462692, rs2479409, rs2495702, rs2542052, rs2543600, rs254487, rs256014, rs25673, rs2569208, rs2573905, rs2583124, rs2583125, rs2587736, rs2587748, rs2587803, rs2605100, rs2617167, rs2642442, rs2652834, rs2654602, rs266729, rs2676192, rs2681472, rs2681492, rs2717536, rs2721069, rs2725369, rs2737229, rs2738173, rs2739532, rs275490, rs2755209, rs2755213, rs2764085, rs2764264, rs278600, rs2788015, rs2802292, rs2805533, rs2805535, rs2805543, rs2805562, rs2814944, rs2814982, rs2833485, rs2835342, rs2838809, rs2838810, rs2838816, rs2902940, rs2918418, rs2923084, rs2925979, rs2929282, rs294636, rs2954029, rs2956605, rs2958832, rs2970848, rs2972146, rs3091244, rs3124736, rs3127162, rs3133926, rs3136441, rs3177928, rs3219142, rs33083, rs337656, rs340874, rs35767, rs361147, rs362356, rs3742264, rs3745833, rs3750847, rs3757354, rs3763305, rs3764261, rs3784131, rs3785977, rs3788157, rs3790426, rs3795437, rs3800231, rs380092, rs3803304, rs381815, rs3851179, rs386000, rs3898610, rs3923972, rs405509, rs4073968, rs4128764, rs4129767, rs4129933, rs414743, rs4148008, rs4149268, rs4149313, rs4149497, rs42294, rs4279252, rs4285687, rs4287919, rs4293393, rs429358, rs4299376, rs4305435, rs4308687, rs4348534, rs4367043, rs4369682, rs4373084, rs4384809, rs439401, rs4402960, rs4420638, rs442177, rs4443878, rs4457053, rs4459178, rs4460176, rs4485702, rs4494555, rs4506565, rs4520070, rs4591494, rs4595985, rs4607103, rs4607517, rs4611001, rs4654910, rs4660293, rs4668356, rs4690810, rs4691183, rs4705038, rs4705423, rs4712523, rs4722094, rs4731702, rs4734457, rs474279, rs4745348, rs4759375, rs4764600, rs4765127, rs4775041, rs4775083, rs4775671, rs4780054, rs479744, rs4802234, rs4815617, rs4820599, rs4843204, rs4846914, rs4856642, rs4861952, rs4871976, rs4874147, rs4884, rs491528, rs4916176, rs492602, rs4943794, rs4946935, rs4968363, rs4977756, rs4982702, rs4982703, rs4982705, rs508001, rs512577, rs514230, rs514708, rs5219, rs5446, rs552148, rs5572, rs5574, rs560887, rs561241, rs562338, rs563694, rs5756931, rs579327, rs581080, rs5882, rs590218, rs5945326, rs597668, rs599839, rs6004864, rs6004867, rs6004887, rs6004890, rs6013029, rs6029526, rs6035189, rs605066, rs605928, rs6065906, rs6070157, rs6087664, rs610160, rs6128112, rs629301, rs641959, rs6432908, rs6433083, rs6441391, rs6450176, rs645040, rs6450853, rs6463843, rs6472566, rs6489992, rs6495056, rs6495122, rs6511720, rs651922, rs6519442, rs6532059, rs657152, rs6588313, rs6656401, rs6669117, rs6683832, rs6686814, rs6690450, rs6700734, rs6710634, rs6713620, rs6721003, rs672316, rs6770065, rs6770257, rs6781716, rs6793693, rs6801173, rs6811874, rs6812745, rs6817112, rs683907, rs6850916, rs6855911, rs6856902, rs687045, rs6882076, rs690232, rs6922269, rs6949152, rs6990397, rs7019241, rs7034200, rs7069102, rs708356, rs713250, rs7134375, rs7134594, rs7155742, rs7163504, rs7164184, rs7170328, rs7177629, rs7180354, rs7192898, rs719756, rs7199196, rs7201268, rs7206971, rs7237695, rs7241918, rs7255436, rs7260463, rs727435, rs728546, rs7310409, rs7319671, rs7321904, rs7324138, rs737337, rs7412, rs744373, rs7504165, rs7515577, rs7517912, rs7531849, rs7564968, rs7570971, rs7571613, rs7578326, rs7578597, rs7581699, rs7584841, rs7590179, rs7620901, rs7621711, rs7624691, rs7640747, rs7654633, rs7655392, rs766410, rs7667236, rs769449, rs7762152, rs7771560, rs7775228, rs7800861, rs780094, rs7813189, rs7825208, rs7826222, rs7903146, rs7907713, rs7909676, rs792376, rs7926335, rs7930940, rs7938734, rs7941030, rs7944584, rs795659, rs7957197, rs7961581, rs7965602, rs7977406, rs7988257, rs8012963, rs8017377, rs8028050, rs8028803, rs8029244, rs8042680, rs8044195, rs8045479, rs8046337, rs8050136, rs8051232, rs806606, rs8079482, rs8083511, rs8091406, rs8093550, rs8136667, rs8176720, rs819228, rs8192678, rs8192708, rs829751, rs838880, rs854523, rs864745, rs871840, rs883484, rs884949, rs886347, rs896854, rs903901, rs911475, rs911847, rs915179, rs917303, rs923520, rs924114, rs9285551, rs9290087, rs9295740, rs9307389, rs9322361, rs9323180, rs936909, rs9377361, rs9377363, rs9400239, rs9411489, rs941604, rs9461011, rs9467160, rs9488822, rs9529500, rs953377, rs954551, rs9576827, rs9594759, rs9620582, rs964184, rs966321, rs9664222, rs966866, rs9686661, rs9696357, rs972283, rs974673, rs9785023, rs980286, rs9804152, rs9813121, rs9815354, rs9825185, rs9831040, rs9831924, rs9866419, rs9868834, rs9871565, rs987237, rs9876363, rs9876608, rs9877938, rs9883089, rs9899404, rs9939609, rs9972931, rs9972933, rs997675, rs9986786, rs9987289, rs9989823 865 more…

Aging: risk reduction for common aging conditions through monitoring & intervention

Objective

Description

Inclusion Criteria

Discussion