Aging: risk reduction for common aging conditions through monitoring & intervention

Objective

Establish baseline markers of wellness and relevant interventions in human aging from a personalized perspective. Intervene in the case of blood-based markers that are out-of-bounds.

Description

A longitudinal personalized aging study. Here is an opportunity to apply the dozens of genome-wide association studies which relate to a variety of general and specific conditions of aging in a comprehensive manner for preventive medicine. Genomic data is linked with corresponding measures of phenotypic or physical biomarkers and testing relevant interventions for phenotype amelioration.

I. Top twenty biological mechanisms of aging in GWAS include: neurodegenerative disease, osteoporosis, IGF-1/Insulin signaling, lipoprotein metabolism, inflammation, immune system function, DNA damage repair, telomere length, transcription (ex: RNA editing), catabolism, mitochondrial health, cell cycle/stem cell health, protein function, blood operations

II. Top twenty phenotypic biomarkers of aging include: blood pressure and hypertension, cholesterol (HDL/LDL/triglycerides; LDL particle size), BMI, Framingham Risk Score, VO2 max, erythrocyte glycoslyation, telomere length, lymphocyte growth capability, granulocyte strength

More information here

Inclusion Criteria

Complete annual blood test (a comprehensive panel of ~50 markers) and provide the data here (ideally through an automated PDF upload). DirectLabs offers the test for less than $100. https://directlabs.com/Home/CWP/tabid/192/language/en-US/Default.aspx
Annual blood test
Potential interventions

Discussion

wamatt

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elvis555

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elvis555

elvis555 joined as a data participant.

oldandangry

oldandangry Blood markers

oldandangry

oldandangry My mother has been through any number of tests - we expect that they will provide sufficient information for the start of this study.

oldandangry

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drdelorenzo

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akrupa

akrupa joined as a data participant.

aaronvollrath

aaronvollrath the required blood test for this study is the direct labs test of the month and is priced at $59.00. if i remember correctly this is about $40 less than the regular price.

melanie

melanie thanks Aaron - you're right, the DirectLabs test is usually marked down in December ($59). i am ordering mine now and will get it fulfilled in early january to capture my annual blood marker levels. https://directlabs.com/ShoppingCart/tabid/2146/language/en-US/Default.aspx

sam

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aaronvollrath

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dschlauch

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wellthcare

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nikolay

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SydneyBennet

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derekja

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jpabello

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oracle3774

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herbaldoc

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herbaldoc

herbaldoc I have some basic labs in my mountain of medical information that go back as far as my birth. CBC, that sort of thing.

gbiggers

gbiggers joined as a data participant.

wreinhardt

wreinhardt joined as a data participant.

EriGentry

EriGentry I'm excited for this study! Many thanks for putting it together! I will have tests done the last week of February. How can I enter data?

melanie

melanie Hopefully the Aging Tracker will allow a csv or text file upload (you may need to convert your PDF), or allow data entry of specific items

EriGentry

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melanie

melanie joined as a data participant.

melanie

melanie added the "Agjng tracker" instrument to this study.